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AIDS-Related Cancers-Kaposi Sarcoma (KS)

Kaposi Sarcoma was first discovered by a Viennese physician called Moritz Kaposi in the late 19th century. It is a low-grade tumor in blood vessels. More recently, Researchers discovered that it was caused by a human herpesvirus 8 (HHV8) virus and discovered cases associated with AIDS. They can be present in the skin and the mouth but can also spread to other organs through the blood.

Patients with this disease usually have elevated purple, pink, brown, black, blue, or red blotches or bumps on many regions of the skin or even the mouth. The disease evolves from early patches into plaques that may subsequently develop into larger, serious tumors. Other signs can be evaluated by measuring blood pressure and performing lab tests. People of any age, including newborn babies, may develop KS.

Researchers investigated various techniques to help reduce the effect of KS on patients or attempt to cure the disease. Palliation medication offers comprehensive treatments that help patients get relief from the disease. Other more effective measures include surgeries, radiation therapy, methods to reduce organ compromise, and relieving psychological stress. Medical researchers are now investigating methods to cure KS thoroughly.


References:

         Kaposi M. Idiopathisces multiples Pigmentsarkom der Haut. Archiv fur Dermatologi und Syphilis. 1872;3:265–273.

         Radu, Oana, Pantanowitz, Liron (2013). Kaposi Sarcoma. Archives of Pathology & Laboratory Medicine. 137(2), 289–294.

        Di Lorenzo G, Konstantinopoulos PA, Pantanowitz L, Di Trolio R, De Placido S, Dezube BJ. Management of AIDS-related Kaposi’s sarcoma. Lancet Oncol. 2007;8(2):167–176




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